17 0 obj 14 0 obj 39 0 obj 0000038278 00000 n 0000044355 00000 n ,������s����0E. ��Cg�L#J[�)Jr�*NAS��Mm4tL�M)Z�S���Us�ku'�i�Ox�Eq����O��=�rq��̥M6;05�еҦ��|���a�����R2ceW+ ChemInform Abstract: Highly Efficient and Selective Photocatalytic Hydrogenation of Functionalized Nitrobenzenes. <<6d9b8e47e17786449e01d05a738c74db>]>> 58 48 0000044143 00000 n 0000044094 00000 n 0000040831 00000 n 0000001196 00000 n . 0000031177 00000 n 0000025289 00000 n 0000003665 00000 n 0 0000029888 00000 n x��!�A�|�)��e�suEP~ֱ֤��a�oW"��d�\��"*��n�N�>��F���!s�t0�]2frS�m3�D8�u�O�È�)Q�n�A>L�Z�V�Fv�~��.�y�ϧ&�S�X�9UjB�V�Q�5�,6�M��i�z��,�8�X8����b0N�@NS� BI8����b��O�w�ʃa���q�9�G�4�҇#xDn��Š����=" ��^q1�G��z�`��G��_9�G�4�Ri�ԕ8��͑Q���x�dAV��d�ΑQ•=,�F����?�"�x�c�1!�ku�����L"|p��W#����kauv`#���phD��ȸ�\��tEM#���ҿ1�z�wq&q��za�/-����7d���#� �p�eI��`��k! 8 0 obj Aromatic amines are an important class of compounds frequently used as key intermediates in the synthesis of pharmaceutical products, dyestuff and polymers 1. Low micromolar IC50 values were exhibited over a panel of three primary GBM patient-derived cell cultures belonging to proneural (GBM-1), mesenchymal (GBM-2), and classical (GBM-3) subtypes. 0000035449 00000 n 0000021435 00000 n 0 0000015331 00000 n ChemInform Abstract: Base-Free Chemoselective Transfer Hydrogenation of Nitroarenes to Anilines with Formic Acid as Hydrogen Source by a Reusable Heterogeneous Pd/ZrP Catalyst. trailer 0000052399 00000 n 6 0 obj Oxygenated carbon species contribute to the formation of CO2 and might be involved in the formation of isocyanates. %���� <>/ProcSet[/PDF/Text/ImageB/ImageC/ImageI]>>/Parent 34 0 R/MediaBox[0 0 595.32 841.92]/Contents 38 0 R/Type/Page>> 0000003020 00000 n 0000035572 00000 n 0000000773 00000 n 0000047142 00000 n 28 15.10: Spectroscopy of Aromatic Compounds IR: Aromatic ring C–H stretching at 3030 cm−1 and 0000033891 00000 n 0000041087 00000 n <>/ProcSet[/PDF/Text/ImageB/ImageC/ImageI]>>/Parent 3 0 R/MediaBox[0 0 595.32 841.92]/Contents 25 0 R/Type/Page>> of deposits on the catalyst was considerably lower for propane. 36 0 obj 0000001786 00000 n Nitration 2.1. ^O�w�q�����%�8O�^�n���N;�}:&�T�tu�Wm���-K������vm������ͮ;�_�{�{��[ �]k�>k���E��6�3߫`�hȖ�{W�;��ļ��2?�}���[���rܷU���+U��)~\} �)������s�v84�P����`RR����p���-�ts�Y����� HR..H. endobj 0000004457 00000 n %%EOF <>/ProcSet[/PDF/Text/ImageB/ImageC/ImageI]>>/Parent 3 0 R/MediaBox[0 0 595.32 841.92]/Contents 28 0 R/Type/Page>> endobj <>/ProcSet[/PDF/Text/ImageB/ImageC/ImageI]>>/Parent 3 0 R/MediaBox[0 0 595.32 841.92]/Contents 7 0 R/Type/Page>> Various nitroaromatics are successfully reduced to amines with 100% conversion and selectivity in methanol at low temperature 0000057194 00000 n 0000020700 00000 n 0000008723 00000 n 0000033184 00000 n <> %PDF-1.4 the deoxygenation of the nitro group proceeds directly by the CO ligand. The IR studies indicate that silica support does not have free –OH group Aromatic Nitro Compound Nitroaromatic compounds are reduced by several nitroreductases, which are flavoprotein enzymes that catalyze the stepwise addition of up to six electrons, though the major metabolite is normally the Artikel I. HYDROGENATION OF AROMATIC NITRO-COMPOUNDS R = H, CH3, i-Pr, OH, OMe, OEt, NH2, COOH 2,4-Dinitrotoluene 2,4-Diaminotoluene 2,4,6-Trinitrotoluene (TNT) 2,4,6-Triaminotoluene 1,3-Dinitrobenzene m-Phenylendiamine R NO2 R NH2 NO2 NO2 … 0000044279 00000 n 0000017929 00000 n 0000052806 00000 n Both trinuclear complexes function as efficient reusable heterogeneous catalysts for the selective reduction of assorted nitro compounds to the corresponding amines. Eight compounds showed excellent selectivity indices for GBM cells comparing to a normal astrocyte cell line. 0000017097 00000 n 0000002008 00000 n 0000004594 00000 n <>/ProcSet[/PDF/Text/ImageB/ImageC/ImageI]>>/Parent 3 0 R/MediaBox[0 0 595.32 841.92]/Contents 19 0 R/Type/Page>> 0000002433 00000 n 3 0 obj 0000028345 00000 n 5 0 obj 0000032582 00000 n Other potentially reducible groups such as carbonyl, ester, azide, tosyl, alkenic substituents were unaffected during reaction. endobj 0000017692 00000 n flow hydrogenation reactions of aromatic nitro compounds using novel polysilane-supported palladium catalysts that we recently developed [4a, 4d, 5b, 7]. endobj 0000001057 00000 n III. 0000038846 00000 n 3 0 obj endobj In JC-1 assay, analogues 11, 12, 20, 22, and 24 exerted promising rates of mPTP opening induction towards proneural GBM subtype. %%EOF 0000001877 00000 n These β-C-glycopyranosides hold great promise in medicinal chemistry. The nitro group is also strongly electron-withdrawing. 2 0 obj 85 45 <>/ProcSet[/PDF/Text/ImageB/ImageC/ImageI]>>/Parent 3 0 R/MediaBox[0 0 595.32 841.92]/Contents 16 0 R/Type/Page>> 0000044172 00000 n 0000044069 00000 n %PDF-1.4 %���� 21 0 obj <> endobj xref 21 19 0000000016 00000 n endobj 0000044330 00000 n 0000000016 00000 n <>/Length 2592>>stream The flow system is … This work presents synthesis and characterization of trinuclear {Co 2+ –Co 3+ –Co 2+ } and {Co 2+ –Fe 3+ –Co 2+ } complexes with accessible peripheral Co(II) ions. corresponding aromatic nitro compounds using diammonium hydrogen phosphite in the presence of zinc dust. Low micromolar IC50 values were exhibited over a panel of three primary glioblastoma multiforme patient-derived cell cultures belonging to proneural (GBM-1), mesenchymal (GBM-2), and classical (GBM-3) subtypes. 0000021047 00000 n endobj %PDF-1.4 xref Recycling automobile wastes into a catalyst for organic reactions will offer both environmental protection and economic advantages. Simple, rapid, clean and environmentally benign synthesis of aromatic nitro compounds by using inorganic nitrates as nitrating agents adsorbed on silica gel as a solid support has been reported. 0000025747 00000 n startxref 0000039558 00000 n Isocyanates associated with Ni were identified as reactive intermediates during the reduction of NO to N2.